Nodal Promotes the Self-Renewal of Human Colon Cancer Stem Cells via an Autocrine Manner through Smad2/3 Signaling Pathway

Colorectal cancer is one of the most common and fatal tumors. However, molecular mechanisms underlying carcinogenesis of colorectal cancer remain largely undefined. Here, we explored the expression and function of Nodal in colon cancer stem cells (CCSCs). Nodal and its receptors were present in nume...

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Detalhes bibliográficos
Principais autores: Yuehua Gong, Ying Guo, Yanan Hai, Hao Yang, Yang Liu, Shi Yang, Zhenzhen Zhang, Meng Ma, Linhong Liu, Zheng Li, Zuping He
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2014-01-01
coleção:BioMed Research International
Acesso em linha:http://dx.doi.org/10.1155/2014/364134
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