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Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells
Colorectal cancer is ranked among the top leading causes of cancer death in industrialized populations. Polycomb group proteins (PcGs), including Suz12 and Ezh2, are epigenetic regulatory proteins that act as transcriptional repressors of many differentiation-associated genes and are overexpressed i...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3947628/ https://ncbi.nlm.nih.gov/pubmed/23001792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24224 |
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