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Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.
The BCL6 gene codes for a zinc-finger transcription factor and is involved in chromosomal rearrangements in 30-40% of diffuse large-cell lymphoma (DLCL). These rearrangements cluster within the 5' regulatory region of BCL6 spanning its first non-coding exon. To determine the functional conseque...
Gespeichert in:
| Veröffentlicht in: | EMBO J |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
1995
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8557040/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00311.x |
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