Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.

The BCL6 gene codes for a zinc-finger transcription factor and is involved in chromosomal rearrangements in 30-40% of diffuse large-cell lymphoma (DLCL). These rearrangements cluster within the 5' regulatory region of BCL6 spanning its first non-coding exon. To determine the functional conseque...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:EMBO J
Autori principali: Ye, B H, Chaganti, S, Chang, C C, Niu, H, Corradini, P, Chaganti, R S, Dalla-Favera, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 1995
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8557040/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00311.x
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