Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma.

The BCL6 gene codes for a zinc-finger transcription factor and is involved in chromosomal rearrangements in 30-40% of diffuse large-cell lymphoma (DLCL). These rearrangements cluster within the 5' regulatory region of BCL6 spanning its first non-coding exon. To determine the functional conseque...

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Main Authors: Ye, B H, Chaganti, S, Chang, C C, Niu, H, Corradini, P, Chaganti, R S, Dalla-Favera, R
Format: Artigo
Jezik:Inglês
Izdano: 1995
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC394745/
https://ncbi.nlm.nih.gov/pubmed/8557040
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