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BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor.

Approximately 40% of diffuse large cell lymphoma are associated with chromosomal translocations that deregulate the expression of the BCL6 gene by juxtaposing heterologous promoters to the BCL-6 coding domain. The BCL6 gene encodes a 95-kDa protein containing six C-terminal zinc-finger motifs and an...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Chang, C C, Ye, B H, Chaganti, R S, Dalla-Favera, R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692924/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.6947
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