Evidence for factor IX-independent roles for factor XIa in blood coagulation

BACKGROUND: Factor (f) XIa is traditionally assigned a role in fIX activation during coagulation. However, recent evidence suggests this protease may have additional plasma substrates. OBJECTIVE: To determine if fXIa promotes thrombin generation and coagulation in plasma in the absence of fIX, and t...

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Bibliografiske detaljer
Main Authors: Matafonov, Anton, Cheng, Qiufang, Geng, Yipeng, Verhamme, Ingrid M., Umunakwe, Obi, Tucker, Erik I., Sun, Mao-fu, Serebrov, Vladimir, Gruber, Andras, Gailani, David
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947433/
https://ncbi.nlm.nih.gov/pubmed/24152424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.12435
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