Obesity Induced a Leptin-Notch Signaling Axis in Breast Cancer

To investigate whether obesity induces a leptin–Notch signaling axis in breast cancer (BC), leptin-induced Notch was determined in human MCF-7 and MDA-MB231 and mouse E0771 cells and, in E0771-BC hosted by syngeneic lean and diet-induced-obesity (DIO) C57BL/6J female mice. Lean and DIO-mice were tre...

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Main Authors: Battle, Monica, Gillespie, Corey, Quarshie, Alexander, Lanier, Viola, Harmon, Tia, Wilson, Kaamilah, Torroella-Kouri, Marta, Gonzalez-Perez, Ruben R.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947126/
https://ncbi.nlm.nih.gov/pubmed/24114531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.28496
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