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Leptin-Notch axis impairs 5-fluorouracil effects on pancreatic cancer
5-FU chemotherapy is a current strategy to treat pancreatic cancer (PC), but unfortunately chemoresistance is eventually developed in most patients. Obesity is a risk factor for PC that could affect 5-FU effectiveness through the adipokine leptin, which is a known proliferation, survival factor and...
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| Pubblicato in: | Oncotarget |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5915069/ https://ncbi.nlm.nih.gov/pubmed/29719602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24435 |
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