Leptin-Notch signaling axis is involved in pancreatic cancer progression

Pancreatic cancer (PC) shows a high death rate. PC incidence and prognosis are affected by obesity, a pandemic characterized by high levels of leptin. Notch is upregulated by leptin in breast cancer. Thus, leptin and Notch crosstalk could influence PC progression. Here we investigated in PC cell lin...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Harbuzariu, Adriana, Rampoldi, Antonio, Daley-Brown, Danielle S, Candelaria, Pierre, Harmon, Tia L, Lipsey, Crystal C, Beech, Derrick J, Quarshie, Alexander, Ilies, Gabriela Oprea, Gonzalez-Perez, Ruben R
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352357/
https://ncbi.nlm.nih.gov/pubmed/27999190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13946
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