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Leptin-Notch signaling axis is involved in pancreatic cancer progression

Pancreatic cancer (PC) shows a high death rate. PC incidence and prognosis are affected by obesity, a pandemic characterized by high levels of leptin. Notch is upregulated by leptin in breast cancer. Thus, leptin and Notch crosstalk could influence PC progression. Here we investigated in PC cell lin...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Harbuzariu, Adriana, Rampoldi, Antonio, Daley-Brown, Danielle S, Candelaria, Pierre, Harmon, Tia L, Lipsey, Crystal C, Beech, Derrick J, Quarshie, Alexander, Ilies, Gabriela Oprea, Gonzalez-Perez, Ruben R
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5352357/
https://ncbi.nlm.nih.gov/pubmed/27999190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13946
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