Alkylation Damage by Lipid Electrophiles Targets Functional Protein Systems

Protein alkylation by reactive electrophiles contributes to chemical toxicities and oxidative stress, but the functional impact of alkylation damage across proteomes is poorly understood. We used Click chemistry and shotgun proteomics to profile the accumulation of proteome damage in human cells tre...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Codreanu, Simona G., Ullery, Jody C., Zhu, Jing, Tallman, Keri A., Beavers, William N., Porter, Ned A., Marnett, Lawrence J., Zhang, Bing, Liebler, Daniel C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945913/
https://ncbi.nlm.nih.gov/pubmed/24429493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.032953
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky