RACK1 modulates NF-κB activation by interfering with the interaction between TRAF2 and the IKK complex

The transcription factor NF-κB plays a pivotal role in innate immunity in response to a variety of stimuli, and the coordinated regulation of this pathway determines the proper host responses to extracellular signals. In this study, we identified RACK1 as a novel negative regulator of NF-κB signalin...

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Autores principales: Yao, Fan, Long, Ling-Yun, Deng, Yue-Zhen, Feng, Yuan-Yuan, Ying, Guo-Yuan, Bao, Wen-Dai, Li, Guo, Guan, Dong-Xian, Zhu, Yin-Qiu, Li, Jing-Jing, Xie, Dong
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945882/
https://ncbi.nlm.nih.gov/pubmed/24323043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.162
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