TRAF6 neddylation drives inflammatory arthritis by increasing NF-κB activation

Neddylation is a process similar to ubiquitination, and is critical in various inflammatory diseases; however, its importance in the pathogenesis of inflammatory arthritis is not well understood. Here, we investigated the role of neddylation in collagen-induced arthritis (CIA) and its clinical relev...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Liu, Kewei, Chen, Kaizhe, Zhang, Qian, Zhang, Lianfang, Yan, Yufei, Guo, Changjun, Qi, Jin, Yang, Kai, Wang, Fei, Huang, Ping, Guo, Lei, Deng, Lianfu, Li, Changwei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6484715/
https://ncbi.nlm.nih.gov/pubmed/30626891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-018-0175-8
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