NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK

Tight regulation of NF-κB signaling is essential for innate and adaptive immune responses, yet the molecular mechanisms responsible for its negative regulation are not completely understood. Here we report that NLRX1, a NOD-like receptor family member, negatively regulates Toll-like receptor-mediate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Xia, Xiaojun, Cui, Jun, Wang, Helen Y., Zhu, Liang, Matsueda, Satoko, Wang, Qinfu, Yang, Xiaoang, Hong, Jun, Songyang, Zhou, Chen, Zhijian J., Wang, Rong-Fu
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150212/
https://ncbi.nlm.nih.gov/pubmed/21703539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.02.022
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados