TIFA activates IκB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6

TRAF6 (tumor necrosis factor receptor-associated factor 6) is a RING (really interesting new gene) domain ubiquitin (Ub) ligase that mediates the activation of protein kinases, such as transforming growth factor β-activated kinase (TAK1) and IκB kinase (IKK), by catalyzing the formation of a unique...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ea, Chee-Kwee, Sun, Lijun, Inoue, Jun-Ichiro, Chen, Zhijian J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2004
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15492226/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404132101
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