TIFA activates IκB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6
TRAF6 (tumor necrosis factor receptor-associated factor 6) is a RING (really interesting new gene) domain ubiquitin (Ub) ligase that mediates the activation of protein kinases, such as transforming growth factor β-activated kinase (TAK1) and IκB kinase (IKK), by catalyzing the formation of a unique...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC524439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15492226/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404132101 |
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