Ligand-Dependent Dynamics of the Active-Site Lid in Bacterial Dimethylarginine Dimethylaminohydrolase

[Image: see text] The dimethylarginine dimethylaminohydrolase (DDAH) enzyme family has been the subject of substantial investigation as a potential therapeutic target for the regulation of vascular tension. DDAH enzymes catalyze the conversion of asymmetric N(η),N(η)-dimethylarginine (ADMA) to l-cit...

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Autors principals: Rasheed, Masooma, Richter, Christine, Chisty, Liisa T., Kirkpatrick, John, Blackledge, Martin, Webb, Martin R., Driscoll, Paul C.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945819/
https://ncbi.nlm.nih.gov/pubmed/24484052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4015924
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