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Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia
Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide (NO) synthase, has been proposed to be a mediator of vascular dysfunction during hyperhomocysteinemia. Levels of ADMA are regulated by dimethylarginine dimethylaminohydrolase (DDAH). Using both in vitro and in vivo approache...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519228/ https://ncbi.nlm.nih.gov/pubmed/18567702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01348.2007 |
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