Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell

Pancreatic β cells adapt to compensate for increased metabolic demand during insulin resistance. Although the microRNA pathway has an essential role in β cell proliferation, the extent of its contribution is unclear. Here, we report that miR-184 is silenced in the pancreatic islets of insulin-resist...

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Main Authors: Tattikota, Sudhir G., Rathjen, Thomas, McAnulty, Sarah J., Wessels, Hans-Hermann, Akerman, Ildem, van de Bunt, Martijn, Hausser, Jean, Esguerra, Jonathan L.S., Musahl, Anne, Pandey, Amit K., You, Xintian, Chen, Wei, Herrera, Pedro L., Johnson, Paul R., O’Carroll, Donal, Eliasson, Lena, Zavolan, Mihaela, Gloyn, Anna L., Ferrer, Jorge, Shalom-Feuerstein, Ruby, Aberdam, Daniel, Poy, Matthew N.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945818/
https://ncbi.nlm.nih.gov/pubmed/24361012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.11.015
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