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Kinetics of Tumor Destruction by Chimeric Antigen Receptor-modified T Cells
The use of chimeric antigen receptor (CAR)–modified T cells as a therapy for hematologic malignancies and solid tumors is becoming more widespread. However, the infusion of a T-cell product targeting a single tumor-associated antigen may lead to target antigen modulation under this selective pressur...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3945803/ https://ncbi.nlm.nih.gov/pubmed/24213558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.262 |
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