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Modification of Hyaluronan by Heavy Chains of Inter-α-Inhibitor in Idiopathic Pulmonary Arterial Hypertension

We previously reported an altered hyaluronan (HA) metabolism in idiopathic pulmonary arterial hypertension (IPAH) lung tissue and cultured smooth muscle cells. Hyaluronan was present in the smooth muscle cell layer surrounding the pulmonary vasculature and in plexigenic lesions. Additionally, cultur...

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Autori principali: Lauer, Mark E., Aytekin, Metin, Comhair, Suzy A., Loftis, Jacqueline, Tian, Liping, Farver, Carol F., Hascall, Vincent C., Dweik, Raed A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945340/
https://ncbi.nlm.nih.gov/pubmed/24403074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.512491
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