Telomere elongation in immortal human cells without detectable telomerase activity.

Immortalization of human cells is often associated with reactivation of telomerase, a ribonucleoprotein enzyme that adds TTAGGG repeats onto telomeres and compensates for their shortening. We examined whether telomerase activation is necessary for immortalization. All normal human fibroblasts tested...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	EMBO J
Päätekijät:	Bryan, T M, Englezou, A, Gupta, J, Bacchetti, S, Reddel, R R
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Publishing Group 1995
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7556065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00098.x
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