Telomere elongation in immortal human cells without detectable telomerase activity.

Immortalization of human cells is often associated with reactivation of telomerase, a ribonucleoprotein enzyme that adds TTAGGG repeats onto telomeres and compensates for their shortening. We examined whether telomerase activation is necessary for immortalization. All normal human fibroblasts tested...

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Bibliographic Details

Published in:	EMBO J
Main Authors:	Bryan, T M, Englezou, A, Gupta, J, Bacchetti, S, Reddel, R R
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 1995
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394507/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7556065/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb00098.x
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