Pharmacological activation of NQO1 increases NAD(+) levels and attenuates cisplatin-mediated acute kidney injury in mice

Cisplatin is a widely used chemotherapeutic agent for the treatment of various tumors. In addition to its antitumor activity, cisplatin affects normal cells and may induce adverse effects, such as ototoxicity, nephrotoxicity, and neuropathy. Various mechanisms, such as DNA adduct formation, mitochon...

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Detaylı Bibliyografya
Asıl Yazarlar: Oh, Gi-Su, Kim, Hyung-Jin, Choi, Jae-Hyuck, Shen, AiHua, Choe, Seong-Kyu, Karna, Anzani, Lee, Seung Hoon, Jo, Hyang-Jeong, Yang, Sei-Hoon, Kwak, Tae Hwan, Lee, Chul-Ho, Park, Raekil, So, Hong-Seob
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Basic Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944666/
https://ncbi.nlm.nih.gov/pubmed/24025646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.330
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