Pharmacological activation of NQO1 increases NAD(+) levels and attenuates cisplatin-mediated acute kidney injury in mice

Cisplatin is a widely used chemotherapeutic agent for the treatment of various tumors. In addition to its antitumor activity, cisplatin affects normal cells and may induce adverse effects, such as ototoxicity, nephrotoxicity, and neuropathy. Various mechanisms, such as DNA adduct formation, mitochon...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Oh, Gi-Su, Kim, Hyung-Jin, Choi, Jae-Hyuck, Shen, AiHua, Choe, Seong-Kyu, Karna, Anzani, Lee, Seung Hoon, Jo, Hyang-Jeong, Yang, Sei-Hoon, Kwak, Tae Hwan, Lee, Chul-Ho, Park, Raekil, So, Hong-Seob
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group 2014
Θέματα:
Basic Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944666/
https://ncbi.nlm.nih.gov/pubmed/24025646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2013.330
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