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Primary over-expression of AβPP in muscle does not lead to the development of inclusion body myositis in a new lineage of the MCK-AβPP transgenic mouse

The aim of this study is to determine whether primary over-expression of AβPP in skeletal muscle results in the development of features of inclusion body myositis (IBM) in a new lineage of the MCK-AβPP transgenic mouse. Quantitative histological, immunohistochemical and western blotting studies were...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Luo, Yue-Bei, Johnsen, Russell D, Griffiths, Lisa, Needham, Merrilee, Fabian, Victoria A, Fletcher, Sue, Wilton, Steve D, Mastaglia, Frank L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2013
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944453/
https://ncbi.nlm.nih.gov/pubmed/24205796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12048
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