Design of a Novel Integration-deficient Lentivector Technology That Incorporates Genetic and Posttranslational Elements to Target Human Dendritic Cells

As sentinels of the immune system, dendritic cells (DCs) play an essential role in regulating cellular immune responses. One of the main challenges of developing DC-targeted therapies includes the delivery of antigen to DCs in order to promote the activation of antigen-specific effector CD8 T cells....

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Detalhes bibliográficos
Main Authors: Tareen, Semih U, Kelley-Clarke, Brenna, Nicolai, Christopher J, Cassiano, Linda A, Nelson, Lisa T, Slough, Megan M, Vin, Chintan D, Odegard, Jared M, Sloan, Derek D, Van Hoeven, Neal, Allen, James M, Dubensky, Thomas W, Robbins, Scott H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944334/
https://ncbi.nlm.nih.gov/pubmed/24419083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.278
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