Oral Delivery of Bioencapsulated Proteins Across Blood–Brain and Blood–Retinal Barriers

Delivering neurotherapeutics to target brain-associated diseases is a major challenge. Therefore, we investigated oral delivery of green fluorescence protein (GFP) or myelin basic protein (MBP) fused with the transmucosal carrier cholera toxin B subunit (CTB), expressed in chloroplasts (bioencapsula...

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Autors principals: Kohli, Neha, Westerveld, Donevan R, Ayache, Alexandra C, Verma, Amrisha, Shil, Pollob, Prasad, Tuhina, Zhu, Ping, Chan, Sic L, Li, Qiuhong, Daniell, Henry
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944331/
https://ncbi.nlm.nih.gov/pubmed/24281246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.273
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