Oral Delivery of Angiotensin-Converting Enzyme 2 and Angiotensin-(1-7) Bioencapsulated in Plant Cells Attenuates Pulmonary Hypertension

Emerging evidences indicate that diminished activity of the vasoprotective axis of the renin–angiotensin system, constituting angiotensin-converting enzyme 2 (ACE2) and its enzymatic product, angiotensin-(1-7) [Ang-(1-7)] contribute to the pathogenesis of pulmonary hypertension (PH). However, long-t...

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Detalhes bibliográficos
Publicado no:Hypertension
Main Authors: Shenoy, Vinayak, Kwon, Kwang-Chul, Rathinasabapathy, Anandharajan, Lin, Shina, Jin, Guiying, Song, Chunjuan, Shil, Pollob, Nair, Anand, Qi, Yanfei, Li, Qiuhong, Francis, Joseph, Katovich, Michael J., Daniell, Henry, Raizada, Mohan K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239698/
https://ncbi.nlm.nih.gov/pubmed/25225206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.114.03871
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