Oral Delivery of ACE2/Ang-(1–7) Bioencapsulated in Plant Cells Protects against Experimental Uveitis and Autoimmune Uveoretinitis

Hyperactivity of the renin-angiotensin system (RAS) resulting in elevated Angiotensin II (Ang II) contributes to all stages of inflammatory responses including ocular inflammation. The discovery of angiotensin-converting enzyme 2 (ACE2) has established a protective axis of RAS involving ACE2/Ang-(1–...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Shil, Pollob K, Kwon, Kwang-Chul, Zhu, Ping, Verma, Amrisha, Daniell, Henry, Li, Qiuhong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429699/
https://ncbi.nlm.nih.gov/pubmed/25228068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.179
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