Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence

Oncogenic stress-induced senescence (OIS) prevents the ability of oncogenic signals to induce tumorigenesis. It is now largely admitted that the mitogenic effect of oncogenes requires metabolic adaptations to respond to new energetic and bio constituent needs. Yet, whether glucose metabolism affects...

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Bibliographic Details
Main Authors: Gitenay, D, Wiel, C, Lallet-Daher, H, Vindrieux, D, Aubert, S, Payen, L, Simonnet, H, Bernard, D
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944274/
https://ncbi.nlm.nih.gov/pubmed/24577087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.63
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