Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence

Oncogenic stress-induced senescence (OIS) prevents the ability of oncogenic signals to induce tumorigenesis. It is now largely admitted that the mitogenic effect of oncogenes requires metabolic adaptations to respond to new energetic and bio constituent needs. Yet, whether glucose metabolism affects...

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Bibliografiske detaljer
Main Authors: Gitenay, D, Wiel, C, Lallet-Daher, H, Vindrieux, D, Aubert, S, Payen, L, Simonnet, H, Bernard, D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944274/
https://ncbi.nlm.nih.gov/pubmed/24577087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.63
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