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Acute Regulation of Cardiac Metabolism by the Hexosamine Biosynthesis Pathway and Protein O-GlcNAcylation

OBJECTIVE: The hexosamine biosynthesis pathway (HBP) flux and protein O-linked N-acetyl-glucosamine (O-GlcNAc) levels have been implicated in mediating the adverse effects of diabetes in the cardiovascular system. Activation of these pathways with glucosamine has been shown to mimic some of the diab...

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Bibliografiske detaljer
Main Authors: Laczy, Boglárka, Fülöp, Norbert, Onay-Besikci, Arzu, Des Rosiers, Christine, Chatham, John C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073970/
https://ncbi.nlm.nih.gov/pubmed/21494549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018417
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