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Activation of the hexosamine biosynthesis pathway and protein O-GlcNAcylation modulate hypertrophic and cell signaling pathways in cardiomyocytes from diabetic mice

Patients with diabetes have a much greater risk of developing heart failure than non-diabetic patients, particularly in response to an additional hemodynamic stress such as hypertension or infarction. Previous studies have shown that increased glucose metabolism via the hexosamine biosynthesis pathw...

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Hlavní autoři: Marsh, Susan A., Dell'Italia, Louis J., Chatham, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3025273/
https://ncbi.nlm.nih.gov/pubmed/20676904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-010-0699-8
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