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Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart

AIMS: Increased O-linked attachment of β-N-acetylglucosamine (O-GlcNAc) to proteins has been implicated in the adverse effects of diabetes on the heart, although this has typically been based on models of severe hyperglycemia. Diabetes has also been associated with dysregulation of autophagy, a crit...

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Detalhes bibliográficos
Main Authors: Marsh, Susan A., Powell, Pamela C., Dell’Italia, Louis J., Chatham, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477499/
https://ncbi.nlm.nih.gov/pubmed/22728715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.06.011
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