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Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart

AIMS: Increased O-linked attachment of β-N-acetylglucosamine (O-GlcNAc) to proteins has been implicated in the adverse effects of diabetes on the heart, although this has typically been based on models of severe hyperglycemia. Diabetes has also been associated with dysregulation of autophagy, a crit...

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Главные авторы: Marsh, Susan A., Powell, Pamela C., Dell’Italia, Louis J., Chatham, John C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477499/
https://ncbi.nlm.nih.gov/pubmed/22728715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.06.011
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