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Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart

AIMS: Increased O-linked attachment of β-N-acetylglucosamine (O-GlcNAc) to proteins has been implicated in the adverse effects of diabetes on the heart, although this has typically been based on models of severe hyperglycemia. Diabetes has also been associated with dysregulation of autophagy, a crit...

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Hlavní autoři: Marsh, Susan A., Powell, Pamela C., Dell’Italia, Louis J., Chatham, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477499/
https://ncbi.nlm.nih.gov/pubmed/22728715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.06.011
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