Glucose metabolism and hexosamine pathway regulate oncogene-induced senescence

Oncogenic stress-induced senescence (OIS) prevents the ability of oncogenic signals to induce tumorigenesis. It is now largely admitted that the mitogenic effect of oncogenes requires metabolic adaptations to respond to new energetic and bio constituent needs. Yet, whether glucose metabolism affects...

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Detalhes bibliográficos
Main Authors: Gitenay, D, Wiel, C, Lallet-Daher, H, Vindrieux, D, Aubert, S, Payen, L, Simonnet, H, Bernard, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944274/
https://ncbi.nlm.nih.gov/pubmed/24577087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.63
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