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Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc
Shc (Src homology 2 domain containing) adaptors are ubiquitous components of the signaling pathways triggered by tyrosine kinase-coupled receptors. In lymphocytes, similar to other cell types, the p52 and p66 isoforms of ShcA/Shc participate in a self-limiting loop where p52Shc acts as a positive re...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944259/ https://ncbi.nlm.nih.gov/pubmed/24556683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.44 |
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