Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc

Shc (Src homology 2 domain containing) adaptors are ubiquitous components of the signaling pathways triggered by tyrosine kinase-coupled receptors. In lymphocytes, similar to other cell types, the p52 and p66 isoforms of ShcA/Shc participate in a self-limiting loop where p52Shc acts as a positive re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Patrussi, L, Capitani, N, Cannizzaro, E, Finetti, F, Lucherini, O M, Pelicci, P G, Baldari, C T
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2014
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944259/
https://ncbi.nlm.nih.gov/pubmed/24556683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.44
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