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Rational Design of Matrix Metalloproteinase-13 (MMP-13) Activatable Probes for Enhanced Specificity

Due to the important roles of matrix metalloproteinases (MMPs) play in tumor invasion and metastasis, various activatable optical probes have been developed to visualize MMP activities in vitro and in vivo. Our recently developed MMP-13 activatable probe, L-MMP-P12, has been successfully applied to...

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Detalhes bibliográficos
Main Authors: Zhu, Lei, Ma, Ying, Kiesewetter, Dale O, Wang, Ye, Lang, Lixin, Lee, Seulki, Niu, Gang, Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944097/
https://ncbi.nlm.nih.gov/pubmed/24266806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400698s
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