Rational Design of Matrix Metalloproteinase-13 (MMP-13) Activatable Probes for Enhanced Specificity

Due to the important roles of matrix metalloproteinases (MMPs) play in tumor invasion and metastasis, various activatable optical probes have been developed to visualize MMP activities in vitro and in vivo. Our recently developed MMP-13 activatable probe, L-MMP-P12, has been successfully applied to...

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Autori principali: Zhu, Lei, Ma, Ying, Kiesewetter, Dale O, Wang, Ye, Lang, Lixin, Lee, Seulki, Niu, Gang, Chen, Xiaoyuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944097/
https://ncbi.nlm.nih.gov/pubmed/24266806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400698s
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