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Novel (19)F Activatable Probe for the Detection of Matrix Metalloprotease-2 Activity by MRI/MRS

[Image: see text] Matrix metalloproteases (MMPs) have been found to be highly expressed in a variety of malignant tumor tissues. Noninvasive visualization of MMP activity may play an important role in the diagnosis of MMP associated diseases. Here we report the design and synthesis of a set of fluor...

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Dettagli Bibliografici
Pubblicato in:Mol Pharm
Autori principali: Yue, Xuyi, Wang, Zhe, Zhu, Lei, Wang, Yu, Qian, Chunqi, Ma, Ying, Kiesewetter, Dale O., Niu, Gang, Chen, Xiaoyuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224523/
https://ncbi.nlm.nih.gov/pubmed/25271556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500443x
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