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Rational Design of Matrix Metalloproteinase-13 (MMP-13) Activatable Probes for Enhanced Specificity

Due to the important roles of matrix metalloproteinases (MMPs) play in tumor invasion and metastasis, various activatable optical probes have been developed to visualize MMP activities in vitro and in vivo. Our recently developed MMP-13 activatable probe, L-MMP-P12, has been successfully applied to...

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Autors principals: Zhu, Lei, Ma, Ying, Kiesewetter, Dale O, Wang, Ye, Lang, Lixin, Lee, Seulki, Niu, Gang, Chen, Xiaoyuan
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944097/
https://ncbi.nlm.nih.gov/pubmed/24266806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400698s
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