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Structures of pattern recognition receptors reveal molecular mechanisms of autoinhibition, ligand recognition and oligomerization

Pattern recognition receptors (PRRs) are essential sentinels for pathogens or tissue damage and integral components of the innate immune system. Recent structural studies have provided unprecedented insights into the molecular mechanisms of ligand recognition and signal transduction by several PRR f...

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Bibliografiske detaljer
Main Authors: Chuenchor, Watchalee, Jin, Tengchuan, Ravilious, Geoffrey, Xiao, T. Sam
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944054/
https://ncbi.nlm.nih.gov/pubmed/24419035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2013.10.009
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