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Structures of pattern recognition receptors reveal molecular mechanisms of autoinhibition, ligand recognition and oligomerization
Pattern recognition receptors (PRRs) are essential sentinels for pathogens or tissue damage and integral components of the innate immune system. Recent structural studies have provided unprecedented insights into the molecular mechanisms of ligand recognition and signal transduction by several PRR f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3944054/ https://ncbi.nlm.nih.gov/pubmed/24419035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2013.10.009 |
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