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Organocatalytic asymmetric fluorination of α-chloroaldehydes involving kinetic resolution

In a previous study it was shown that the enantioselective α-fluorination of racemic α-chloroaldehydes with a chiral organocatalyst yielded the corresponding α-chloro-α-fluoroaldehydes with high enantioselectivity. It was also revealed that kinetic resolution of the starting aldehydes was involved i...

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Main Authors: Shibatomi, Kazutaka, Okimi, Takuya, Abe, Yoshiyuki, Narayama, Akira, Nakamura, Nami, Iwasa, Seiji
Formato: Artigo
Idioma:Inglês
Publicado: Beilstein-Institut 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943883/
https://ncbi.nlm.nih.gov/pubmed/24605153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.10.30
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