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Organocatalytic enantio- and diastereoselective cycloetherification via dynamic kinetic resolution of chiral cyanohydrins

Enantioselective approaches to synthesize six-membered oxacycles with multiple stereogenic centres are in high demand to enable the discovery of new therapeutic agents. Here we present a concise organocatalytic cycloetherification for the highly enantio- and diastereoselective synthesis of tetrahydr...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Yoneda, Naoki, Fujii, Yuki, Matsumoto, Akira, Asano, Keisuke, Matsubara, Seijiro
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680189/
https://ncbi.nlm.nih.gov/pubmed/29123080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01099-x
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