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Organocatalytic enantio- and diastereoselective cycloetherification via dynamic kinetic resolution of chiral cyanohydrins

Enantioselective approaches to synthesize six-membered oxacycles with multiple stereogenic centres are in high demand to enable the discovery of new therapeutic agents. Here we present a concise organocatalytic cycloetherification for the highly enantio- and diastereoselective synthesis of tetrahydr...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Yoneda, Naoki, Fujii, Yuki, Matsumoto, Akira, Asano, Keisuke, Matsubara, Seijiro
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680189/
https://ncbi.nlm.nih.gov/pubmed/29123080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01099-x
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