One-pot Fluorination and Organocatalytic Robinson Annulation for Asymmetric Synthesis of Mono- and Difluorinated Cyclohexenones

A one-pot fluorination and organocatalytic Robinson annulation sequence has been developed for asymmetric synthesis of 6-fluoroyclohex-2-en-1-ones and 4,6-difluorocyclohex-2-en-1-ones. The reactions promoted by cinchona alkaloid amine afforded products bearing two or three stereocenters in good to e...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Huang, Xin, Zhao, Weizhao, Zhang, Xiaofeng, Liu, Miao, Vasconcelos, Stanley N. S., Zhang, Wei
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
Sujets:
Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6225330/
https://ncbi.nlm.nih.gov/pubmed/30181479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23092251
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires