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USING FLUORODEOXYTHYMIDINE TO MONITOR ANTI-EGFR INHIBITOR THERAPY IN SQUAMOUS CELL CARCINOMA XENOGRAFTS

BACKGROUND: 3′-18F-fluoro-3′-deoxy-fluorothymidine ((18)F-FLT), a nucleoside analog, could monitor effects of molecularly targeted therapeutics on tumor proliferation. METHODS: We tested whether (18)F-FLT positron emission tomography (PET) uptake changes are associated with antitumor effects of erlo...

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Bibliografski detalji
Glavni autori: Atkinson, David M., Clarke, Michelle J., Mladek, Ann C., Carlson, Brett L., Trump, David P., Jacobson, Mark S., Kemp, Brad J., Lowe, Val J., Sarkaria, Jann N.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942889/
https://ncbi.nlm.nih.gov/pubmed/18286491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.20770
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