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Thioredoxin and glutaredoxin-mediated redox regulation of ribonucleotide reductase
Ribonucleotide reductase (RNR), the rate-limiting enzyme in DNA synthesis, catalyzes reduction of the different ribonucleotides to their corresponding deoxyribonucleotides. The crucial role of RNR in DNA synthesis has made it an important target for the development of antiviral and anticancer drugs....
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Baishideng Publishing Group Co., Limited
2014
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3942543/ https://ncbi.nlm.nih.gov/pubmed/24600515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v5.i1.68 |
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