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Thioredoxin and glutaredoxin-mediated redox regulation of ribonucleotide reductase

Ribonucleotide reductase (RNR), the rate-limiting enzyme in DNA synthesis, catalyzes reduction of the different ribonucleotides to their corresponding deoxyribonucleotides. The crucial role of RNR in DNA synthesis has made it an important target for the development of antiviral and anticancer drugs....

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Sonraí Bibleagrafaíochta
Main Authors: Sengupta, Rajib, Holmgren, Arne
Formáid: Artigo
Teanga:Inglês
Foilsithe: Baishideng Publishing Group Co., Limited 2014
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942543/
https://ncbi.nlm.nih.gov/pubmed/24600515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v5.i1.68
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