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Glutathione-glutaredoxin is an efficient electron donor system for mammalian p53R2–R1-dependent ribonucleotide reductase

Deoxyribonucleotides are DNA building blocks and are produced de novo by reduction of ribose to deoxyribose. This reduction is catalyzed by ribonucleotide reductase (RNR), a heterodimeric tetramer enzyme in mammalian cells, having one of two free radical-containing subunits called R2 and p53R2. R2 i...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Sengupta, Rajib, Coppo, Lucia, Mishra, Pradeep, Holmgren, Arne
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709626/
https://ncbi.nlm.nih.gov/pubmed/31266802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008752
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