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A Novel mGluR5 Antagonist, MFZ 10-7, Inhibits Cocaine-Taking and Cocaine-Seeking Behavior in Rats

Preclinical studies suggest that negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 5 (mGluR5), including MPEP (2-methyl-6-(phenylethynyl)pyridine), MTEP (3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine) and fenobam, are highly effective in attenuating drug-taking an...

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Detalhes bibliográficos
Main Authors: Keck, Thomas M., Zou, Mu-Fa, Bi, Guo-Hua, Zhang, Hai-Ying, Wang, Xiao-Fei, Yang, Hong-Ju, Srivastava, Ratika, Gardner, Eliot L., Xi, Zheng-Xiong, Newman, Amy Hauck
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942387/
https://ncbi.nlm.nih.gov/pubmed/24001208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12086
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